Patients with elevated hs-cTnI levels (>40 ng/L) were associated with higher fatality than those with a level of hs-cTnI in the normal range after controlling for age, sex, hypertension, diabetes, and eGFR (adjusted hazard ratio [95% CI]: 4.79 [1.46-15.69]). The gene discussed is TNNI3; the disease is Hypertension.