While previous conventional studies estimate the GLUT1 and GLUT3 of tumors regardless of the heterogeneous cellular subpopulation of tumor tissue, here we scrutinize the expression of GLUT1 and GLUT3 in TME using single-cell RNA-sequencing (scRNA-seq) as well as tumor tissue RNA-sequencing (RNA-seq) data from lung cancer patients. Here, SLC2A3 is linked to lung cancer.