PARP1 and telomere syndrome: Kaplan-Meier analysis indicated that PARP-1 and γH2AX were negatively associated with the event-free survival (EFS) of patients with STS (p < 0.001, Figure 7C, D); in contrast, RAD51 was positively associated with the EFS of patients with STS, which suggested that HRD is a prognostic marker for STS patients (p < 0.0001, Figure 7E).