At last the genes which belong to both DEGs and hub genes are seen as the target genes which highly related to ovarian cancer, and finally 34 genes were selected (ADH1B, BARX1, C7, CADPS, CCL21, CFAP100, CFAP65, COL11A1, COL1A1, COL2A1, COL5A1, COL8A1, COMP, CXCL14, ECEL1, EFCAB1, FMO2, FNDC1, INHBA, LRRC15, NKAIN4, OMD, PLCB1, PLCXD3, SERPINE1, SFRP2, SFRP4, SNTN, SORCS2, SVEP1, THBS2, THBS4, TUBA4B, VCAN). The gene discussed is COL8A1; the disease is ovarian carcinoma.