KMT2A and acute myeloid leukemia: According to the World Health Organization classification system updated in 2008, AML with recurrent genetic abnormalities including t(8;21)(q22;q22), t(11q23)/MLL, t(15;17)(q24;q21), inv(16)(p13.1q22), and t(16;16)(p13.1;q22) has been identified [7, 8].