It has been reported that TN exerts strong inhibitory effects on the expression of fatty acid generating and transporting proteins, such as glucose-6-phosphate dehydrogenase (G6PD), FABP4, LPL and CD36/FAT, CYP27A1, as well as transcription factors, including FXR, PPARγ, and LXR, and in turn, significantly attenuates hepatic inflammation and lipid accumulation in mice with NASH [126]. The gene discussed is G6PD; the disease is metabolic dysfunction-associated steatohepatitis.