After investigation of TRIM28 and LBX2-AS1 expression in TCGA-LGG and TCGA-GBM datasets, it was found that TRIM28 was positively correlated with LBX2-AS1 expression in glioma (Pearson r = 0.300, p < 0.001) (Fig. 4a). This evidence concerns the gene LBX2 and central nervous system cancer.