A recent review summarized the beneficial effects of exercise on NAFLD, in which reducing intrahepatic fat content, increasing β-oxidation of fatty acids, inducing hepato-protective autophagy, overexpressing peroxisome proliferator-activated receptor-γ (PPAR-γ), attenuating hepatocyte inflammation and apoptosis, as well as decreasing oxidative stress had been proposed to be possible mechanisms of exercise effect on NAFLD [77]. The gene discussed is PPARG; the disease is metabolic dysfunction-associated steatotic liver disease.