Furthermore, after adjusting for all potential confounders (age, smoking, previous ischemic stroke, previous coronary heart disease, and body mass index, low‐density lipoprotein, hs‐CRP, HbA1c and HCY level), lower GPx3 activity was identified as an independent predictor of increased mean CIMT (β = −.370, p = .002). Here, GPX3 is linked to ischemic stroke.