SOD1 and amyotrophic lateral sclerosis: A phenotypic screening of ebselen, edaravone and nine lead compounds (1, 2, 5, 6, 9, 10, 11-13) has been undertaken in mouse N2a neuronal cells transfected with human wild-type and G93A SOD1, which is the mutant used in representative SOD1-ALS transgenic mice [27].