FKBP5 and major depressive disorder: However, in line with the present findings, several studies reported an association of the major alleles of FKBP5 SNPs with depression (Zobel et al. 2010), suicidal events in depressed patients (Brent et al. 2010), and more depressive symptoms in male adolescents in the context of victimization (VanZomeren-Dohm et al. 2015).