CLCN5 and Hypercalciuria: Hoopes et al. described 13 unrelated males with a Dent disease phenotype (LMWP, hypercalciuria and at least one among nephrocalcinosis, nephrolithiasis, renal insufficiency, hypophosphatemia or hematuria) without any CLCN5 gene mutations (Hoopes et al. 2004).