OCRL and Dent disease: They described 32 unrelated males with a Dent disease phenotype, 19 (about 60%) of them with a mutated CLCN5 gene (DD1), 5 (about 15%) with a mutated OCRL gene (DD2), and 8 (25%) with no mutations in either gene (DD3) (Hoopes et al. 2004, 2005).