Hierarchical clustering of the differentially expressed intracellular DAMPs using Morpheus showed the dysregulated expression of intracellular DAMPs, including elevated expression of galectins (LGALS1 and LGALS1), thioredoxin (TXN and TXN2), S100 proteins (S100A3, S100A4, S100A8 and S100A9 et al), cyclophilin A (PPIA), peroxiredoxin 1(PRDX1) and heat shock proteins (HSPB1, HSPD1 and HSP90B1) in MCT‐induced PAH (Figure 5A). Here, S100A4 is linked to pulmonary arterial hypertension.