Results showed that patients with higher value of NLR (P < .000, HR 20.72, 95% CI 9.460‐45.381), PLR (P < .000, HR 7.09, 95% CI 3.352‐15.001), IL‐6(P < .000, HR 13.73, 95% CI 6.508‐28.981), CRP (P < .000), CT score (P < .000), or who needed nutrition support (P < .000, HR 16.99, 95% CI 7.862‐36.746) or with electrolyte imbalance (P < .000, HR 18.24, 95% CI 8.195‐40.592) than the optimal threshold had a worse outcome, with all‐cause death or received mechanical ventilation. The gene discussed is CRP; the disease is Abnormality of metabolism/homeostasis.