We found that the Immunoreactivity of p‐STAT3 and ratios of the luminal to basal of Mcm2 + cells in the initial negative biopsy tissues were significantly elevated, while the number of MSR1 + cells was significantly lower in those patients who were diagnosed with PCa and HGPCa as compared to those with a benign prostate biopsy (Figure 2A and Table S5). The gene discussed is MSR1; the disease is posterior cortical atrophy.