The ETV6-NTRK3 gene fusion has been described in sporadic solid tumors, including congenital infantile fibrosarcoma (IFS), congenital “cellular” mesoblastic nephroma, secretory breast carcinoma, and carcinoma of the salivary gland (mammary analog secretory carcinoma) in more than 90% of cases and fusion detection has been used as diagnostic confirmation [4–11]. The gene discussed is NTRK3; the disease is congenital fibrosarcoma.