We also identified a large sex-disparity in a non-coding driver event in thyroid cancer (Thy-AdenoCA): TERT promoter mutations were observed in 64% of male-derived samples compared with only 11% of female-derived samples (95% CI: 17–89%, prop-test q = 6.9 × 10−3, LGR q = 0.074, Fig. 1a, Supplementary Fig. 1), again supporting a previous finding17. Here, TERT is linked to thyroid cancer.