Moreover, the 5′ region of the Dmd gene (exons 2 to 20) is one of the mutational hot spots, responsible for Duchenne muscular dystrophy or BMD, that account for ∼15% of all exon deletions and ∼64% of all exon duplications within the Dmd gene (Tuffery-Giraud et al., 2009). Here, DMD is linked to Becker muscular dystrophy.