Remarkably, three of the tumors in this cohort with intraventricular location that had both genetic and epigenetic profiles aligning with RGNT did not have well-defined neurocytic rosettes on either H&E or synaptophysin staining and were best characterized as low-grade oligodendroglial neoplasm NOS based on histologic features. Here, SYP is linked to oligodendroglial tumor.