Moreover, our study confirms that epigenetically confirmed EVN is characterized by frequent FGFR1-TACC1 gene fusion [38], which is rare or absent in other LGNET subtypes including RGNT, DNT, pilocytic astrocytoma, and ganglioglioma both in this cohort and previous studies [29, 31, 33, 34, 36, 44]. Here, TACC1 is linked to pilocytic astrocytoma.