Of note, assessing our cohort, only 6/17 (2 from DS- and 4 from non-DS group) and 2/17 (1 from DS- and 1 from non-DS group; Supplementary file 1) patients with APL, respectively, for the levels of IL-6 and IL-8 became undetectable at D7, such as observed in healthy controls. Here, CXCL8 is linked to acute promyelocytic leukemia.