The distribution of IDH1-IDH2-mutant MDSs in various risk categories was similar to that observed for MDS-WT; however, IDH-mutant MDSs displayed a different cytogenetic pattern, with 60% diploid karyotype, with isolated trisomy 8 in 10% of cases, and other intermediate cytogenetics in 23% of cases [18]. The gene discussed is IDH1; the disease is myelodysplastic syndrome.