IDH2 and acute myeloid leukemia: Di Nardo et al. have reported the preliminary results of a clinical phase II study (NCT 02677922) involving the treatment of 101 adult IDH2-mutant AML patients ineligible to receive intensive chemotherapy, who have been randomized in a 2:1 ratio to receive enasidenib + azacitidine or azacytidine alone [154] (Table 2).