The results showed that the mean BNP concentration was significantly higher in the cardioembolic group than in the other 3 stroke subtypes: (1) large artery atherosclerosis; (2) small artery occlusion (e.g., lacunar); and (3) stroke of other determined etiology or stroke of other undetermined etiology (p < 0.01). The gene discussed is NPPB; the disease is stroke disorder.