NPPB and cardioembolic stroke: Also, when BNP was added to other well-known risk factors, the ability to predict cardioembolic stroke significantly improved: 4-year follow-up, p = 0.018; 8-year follow-up, p = 0.009; net reclassification improvement = 0.968, p < 0.0001: integrated discrimination improvement = 0.039, p < 0.05.