Two molecules, methyltransferase‐like protein 3 (METTL3) and insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1), were found to play crucial roles in potentiating resistance to CDDP through m6A methylation of transcription factor‐activating enhancer‐binding protein 2C (TFAP2C) in seminoma. Here, METTL3 is linked to seminoma.