The Sgo1−/+ mouse brains differentially expressed genes associated with neuronal functions and human AD, including Activity‐regulated cytoskeleton‐associated protein (ARC/Arg3.1) and Early B‐cell Factor 3 (EBF3) in old age (24 months) (Rao, Farooqui, Zhang, et al., 2018). The gene discussed is ARC; the disease is Alzheimer disease.