Therefore, the 138 genes were classified as two clusters: the genes of Cluster I are regulated probably by other transcription factors at 4 hours and by the TEAD/EGL-44-YAP-1/YAP complex at 24 hours, while the genes of Cluster II are regulated mainly by the TEAD/EGL-44-YAP-1/YAP complex at 24 hours during P. aeruginosa PA14 infection. The gene discussed is YAP1; the disease is infection.