Furthermore, we found that miR-4490 mimics decreasedMMP2, vimentin, N-cadherin and ZEB1 expression levels and increased E-cadherinand γ-catenin expression levels, whereas miR-4490 inhibition increased MMP2,vimentin, N-cadherin and ZEB1 expression levels and decreased E-cadherin andγ-catenin expression levels as determined by Western blot analysis in GC cells(Fig. 3d). The gene discussed is CDH1; the disease is gastric cancer.