Interestingly, the association between FGF23 and adverse outcomes in diabetes seems to extend beyond patients with impaired kidney function, as the majority of patients in some of the studies summarized in Table 3 had an eGFR > 60 mL/min/1.73 m2, and in two studies, the average eGFR was even > 90 mL/min/1.73 m2 [53, 54]. This evidence concerns the gene FGF23 and diabetes mellitus.