As no previous studies have assessed the roles of TFAP2B, AP-1 and JAZF1 expression in patients with papillary carcinoma of the thyroid, we aimed to assess TFAP2B, AP-1 and JAZF1 expression in tissues from patients with such cancer correlation their expression with clinic-pathological findings of the tumor and prognostic and follow-up findings of patients. The gene discussed is JAZF1; the disease is thyroid gland papillary carcinoma.