JAZF1 and nodular goiter: We showed that JAZF1 was down-regulated in papillary thyroid cancer tissues more than adjacent non-neoplastic tissues, which was similar to results of Huang et al., (2019), whose report was the first in exploring tumor suppressor role of JAZF1 in papillary thyroid carcinoma using immunohistochemistry and they stated that expression of JAZF1 in papillary thyroid carcinoma was decreased in comparison with adjacent thyroid tissues or with nodular goiter.