Expression of JAZF1 expression was decreased in samples from papillary thyroid carcinoma more than samples from adjacent non-neoplastic thyroid tissue of the same patients (p=0.004). JAZF1 expression in papillary thyroid cancer tissues is negatively associated with advanced stage (p=0.34), lymph nodes metastases (p=0.005), huge tumor size (0.023), presence of extra-thyroid invasion (p=0.045), multifocality of the tumor (p=0.036), vascular invasion (p=0.007) and capsular invasion (p=0.037) (Table 1 and Figure 3). The gene discussed is JAZF1; the disease is neoplasm.