WT1 and astrocytic tumor: However, the potential utility of WT1 immunohistochemical (IHC) staining to discriminate reactive astrogliosis from astrocytic tumors and to separate the tumors’ grades is still a subject for controversy (Schittenhelm et al., 2008; Rivera-Zengotita and Yachnis, 2012; Kusum and Ramita; 2019; Manocha and Jain, 2019).