MFN2 and Charcot-Marie-Tooth disease type 2A1: Overall, the nestin-cre MFN2T105M mouse model characterized by mutant MFN2 expression in a subset of cell types outside the PNS and CNS recapitulated some crucial phenotypical aspects of CMT2A patients (i.e., perturbations in foot gaiting and mitochondrial number reduction in tibialis muscle), but other aspects seem to be in contrast with other well-described studies.