FABP4 and atherosclerosis: Mice lacking FABP4 (FABP4−/−) are partially protected against the development of atherosclerosis also in obese conditions (Pelton et al. 1999), suggesting that atherosclerosis may be favored by circulating chaperone, perhaps when surpassing certain levels.FABP4 was found in human atherosclerotic plaques and its presence has been associated with vulnerable plaques (Peeters et al. 2011).