Many mechanisms were reported to be involved in CDDP resistance of human gastric cancer, such as miR-101/VEGF-C pathway [8], miR-34a/PI3K/AKT/survivin pathway [9], miR-1271/IGF1R, IRS1, mTOR, BCL2 pathway [10], and circ-FN1/miR-182-5p pathway [7]. The gene discussed is FN1; the disease is gastric cancer.