Thus, we hypothesized that miRNA-26a-5p may play an important role in the regulation of CVD induced by TCDD and Aroclor1254 coexposure treatments by regulating the expression of its target gene TGFBR2. Additionally, TGFBR2 can also regulate cyclin-dependent kinase (CDK) activity by interacting with CCND1, thus playing an important role in cardiovascular disease [51, 52]. Here, CCND1 is linked to cardiovascular disorder.