SLC5A2 and type 2 diabetes mellitus: Studies have measured patients on SGLT2 inhibitors to have low-grade asymptomatic ketonemia [11, 12], and in a Japanese multicenter, randomized, 3-arm parallel comparative study, patients with T2DM assigned to low-carbohydrate diet on luseogliflozin had significantly higher serum ketone bodies than their study counterparts on higher carbohydrate diets [12].