Cyclin-dependent kinase inhibitor 1C (CDKN1C) gene, which encodes the cell cycle inhibitor p57KIP2, has been suggested to be involved in the regulation of several cancer hallmarks such as inducing angiogenesis, and it has been tested as a prognostic factor for various cancers [17, 193], as well as a target of PPAR beta/delta [17]. This evidence concerns the gene CDKN1C and cancer.