CAV1 and Familial prostate cancer: For CCLE data, we stratified prostate cancer cell lines based on mean CAV1 gene expression into either high CAV1 expressing cell lines (log2 values >11 (range 11.01–13.61); HPrEC, DU145, PC-3) or low CAV1 expressing cell lines (log2 values <7 (range 4.16–6.88); NCIH660, MDAPCa2B, LNCaP, VCaP, and CWR22Rv1).