CAV1 and Familial prostate cancer: To this end, we assessed the ability of Cav-1 low (Supplementary Fig. 3a) LNCaP and Cav-1 positive (Fig. 2a) PC-3M and RM-9 prostate cancer cell lines to scavenge extracellular fluorescent 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine (DiI)-conjugated synthetic self-assembled lipid particles (SSALPs).