Furthermore, the expression of TGF-β signaling pathway related molecules was decreased after enforced expression of miR-3614-5p in NSCLC cells, while reintroduction of PGAM1 abolished the suppressive effect of miR-3614-5p mimics on the TGF-β signaling pathway (Fig. 7f). This evidence concerns the gene TGFB1 and non-small cell lung carcinoma.