The decreased LE at right Cerebellum_Crus2, right Cerebellum_Crus6 and Vermis_6, and WD at right Cerebellum_Crus6 suggested that the accumulation of alpha-synuclein GCIs of the MSA may destroy specific networks including the DMN and cerebellum networks [8, 12]. This evidence concerns the gene SNCA and multiple system atrophy.