ESR1 and Familial prostate cancer: Other abundant transcripts in ED cells include asparaginase and isoaspartyl peptidase 1 (ASRGL1) a gene associated with prostate cancer (Pudova et al, 2019), the estrogen receptor (ESR1, Fig 5C) and FXYD domain containing ion transport regulator 2 (FXYD2) that encodes the sodium/potassium-transporting ATPase subunit γ, which is involved in renal transport (Sha et al, 2008) (Fig 5G).