METTL3 and ocular melanoma: A study from Jia and colleagues reported that decreased m6A level in ocular melanoma due to downregulation of METTL3 and upregulation of ALKBH5 predicted earlier recurrence and enhanced aggressiveness and also showed that METTL3-mediated m6A modification promoted the translation of HINT2, a tumor suppressor gene, in a YTHDF1-dependent mechanism [118].