CD8A and neoplasm: A recent study revealed that i.v. injection of amidobenzimidazole (ABZI) (1.5 mg/kg) in immunocompetent mice with established syngeneic colon tumors was able to induce tumor regression, with nearly 80% of the treated group remaining tumor free at the end of the study, and this strong inhibition effect was reversed by CD8+ T-cell depletion [52].