MTOR and Alzheimer disease: In another study, utilizing transcriptome-wide Affymetrix microarrays of the extracted lateral ventricular choroid plexus tissue of AD Braak stage III–VI vs control cases, significant upregulation in genes related to metabolic and immune-related pathways including acute phase response, cytokine, cell adhesion, interferons, Janus Kinase and Signal transducer and activator of transcription protein (JAK-STAT) and Mammalian target of rapamycin (mTOR) were observed.