AKT1 and cancer: Recently, it was found that this compound is a potential therapy of cancer since it inhibits KIT, a type III receptor tyrosine kinase (RTK), known to activate many signal transduction pathways including RAS/ERK (Extracellular Signal-Regulated Kinase), PI3K/AKT or PKB (Phosphoinositide 3-kinase/ Protein kinase B), phospholipase C, JAK/STAT (Janus kinase/signal transducers and activators of transcription), and Src kinase pathways [171].