However, Chen et al. reported that 1,25(OH)2D3 attenuates the induction of EMT by TGF-β in colon carcinoma cells and inhibits SNAIL1 and SNAIL2 expression, the E-cadherin/N-cadherin switch, and the secretion of MMP2 and MMP9 [27]. The gene discussed is CDH1; the disease is colon carcinoma.