In particular, we found a slight decrease of MIF in healthy ones (50 μM H2O2: 508.8 ± 3.8, p < 0.05 and 100 μM H2O2: 749.5 ± 24.8, p < 0.05) and a massive increase in SSc ones (50 μM H2O2: 19,685.0 ± 9135.0, p < 0.01 and 100 μM H2O2: 47,417.0 ± 15,026.0, p < 0.01) (Figure 5E). Here, MIF is linked to systemic sclerosis.