Here, two POC assays (Quantum Blue from Buhlmann (Schönenbuch, Switzerland) and Ridaquick from R-Biopharm (Darmstadt, Germany)) and three ELISA assays (Theradiag (monoclonal vs. polyclonal detection antibody; Croissy Beaubourg, France) and R-biopharm) for monitoring ADA trough levels in Inflammatory Bowel Disease (IBD) patients were compared in a fist cohort of 31 IBD patients. This evidence concerns the gene ADA and inflammatory bowel disease.