Of those lncRNAs, OIP5-AS1 was downregulated in both ovarian and colorectal cancer cell lines, whereas RFPL1S, ZEB1-AS1, and C17orf82 were downregulated in only OC cells with no significant changes in colorectal cancer cell lines, suggesting that MDR-related lncRNAs have both specific and conservative functions among different types of cancers. This evidence concerns the gene ZEB1 and colorectal cancer.