In the present study, FMF cases also had variants in IFNAR1 (NM_000629.2:c.954G > C (p.Trp318Cys)) and in IFNB1 (NM_002176.3:c.498A > G (p.Ile166Met)), which were present in two FMF cases and one FMF case, respectively. This evidence concerns the gene IFNB1 and familial Mediterranean fever.