Although a considerable fraction of ~2000 mutations in the CFTR gene causes CF (Cystic Fibrosis Mutation Database, http://www.genet.sickkids.on.ca/app), their theratyping (i.e., matching medications with mutations) remains incomplete (CFTR2 project, http://cftr2.org) (2). Here, CFTR is linked to cystic fibrosis.