Accumulating evidence identified various genetic variants within the MIR17HG gene, including (rs4284505; g.91349218A>G), (rs17735387; g.91353800G>T), (rs1428; g.91354516C>A), (rs7336610; g.91352883C>T), and (rs72640333; g.91352673T>A) that are destined to be correlated with different disorders involving multiple myeloma,13 breast cancer,4 multiple sclerosis,21 and periapical lesions.20 The gene discussed is MIR17HG; the disease is AL amyloidosis.