Collectively, all the above evidence confirm the role which MIR17HG play in autoimmunity and tissue damage (Figure 1), supporting the potential association of the specified genetic variant with SLE development and severity, as reflected in association of the risky genotype (GG) with a higher frequency of mucocutaneous manifestations and a higher SLEDAI score than the other genotypes in the study population. Here, MIR17HG is linked to Autoimmunity.